Scientists Discover Protein That Reverses Heart Disease In Older Mice


Scientists at Harvard University think they have found a way to possibly reverse the aging process in human organs.

Dr. Richard Lee, Director of the Regenerative Medicine at Brigham and Women’s Hospital, and Amy Wagers, of the Department of Regenerative Biology at Harvard, made the discovery when they were working with younger and older mice.

They took an older mouse with the most common form of human heart failure and merged the mouse’s blood stream with that of a healthy young mouse using a Siamese twin technique known as parabiosis. They found that the older mouse’s diseased heart was able to reverse to a younger healthier condition.

They later identified a protein in the blood of young mice called GDF-11, which diminishes with age. They injected this protein directly into the older mice and had the same positive results. They are using this protein to restore other aging/diseased tissues and organs. Their results are published today in the science journal Cell online.

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Tags: Heart, cell, harvard, science

Comment by Heather Spoonheim on May 10, 2013 at 11:00am

Now all we need is for Monsanto to genetically modify pigs so they can produce bacon that actually restores your heart!  Yay!

Comment by Marvel on May 10, 2013 at 12:40pm

as a cardiologist my jaw is dropping right now ... this is like bringing back the dead .. i love when science make magic tricks :)))

Comment by Dan on May 10, 2013 at 2:10pm

@Marvel, as a heart patient with 2 stents (at 33), ditto.

Comment by Dan on May 10, 2013 at 2:11pm

@Heather, if that happens I may have to start worshipping bacon(again).

Comment by Dale Headley on May 10, 2013 at 4:35pm

So what?  I'm going to die of something, no matter what scientists come up with. A heart attack is among my top 5 preferences of ways to die.  If a mouse could talk, I'm sure it would say the same thing.

Comment by Dan on May 10, 2013 at 4:59pm

@Dale. Have you had one? I've had at least 4 and they aren't exactly quick or as efficient as in the movies.

Comment by RobertPiano on May 10, 2013 at 5:27pm

All of this "regenerative" and stem cell research will result in super-humans. Now, some parts of the body can heal, and others do not. That may change. I predict this technology may become the ultimate survival technique in a future "hostile earth" environment.

Comment by kris feenstra on May 10, 2013 at 8:48pm

I wonder if this would have any potential applications for those suffering from Hutchinson-Gilford progeria syndrome.

Comment by Mienie De Kock on May 25, 2013 at 6:14pm



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