Trying to counteract religious-based legislation in Red States is like fighting a Zerg Rush: even if the Terrans kill dozens of them there will still be another couple hundred that get through and make you lose the game.
This is of course why the counter strategy to a Zerg Rush is Firebats. A stalwart armored defense and heavy assault trooper. The idea applies here. Science is the Firebat and the Federal is the production facility to make them. Using the Federal government to legislate secular policies is the equivalent of creating Firebats to deal with the Zerg.