there seem to be two questions here (it's hard to tell after reading this twice).
1. the title of the thread.
my answer would be that this seems to already be the case with a great many people. they already mistake our consciousness for a soul. they do so in error of course.
2. do you believe that there is some seat of consciousness, some center in the mind from whence consciousness comes?
in a word: no. i suggest Daniel Dennett's Consciousness Explained on this topic. there is no seat of consciousness. consciousness is an emergent property of the brain. if what we mean when we refer to consciousness is the essence of what makes the individual the individual then modern neuroscience has fairly well disproved the notion that there is any kind of center of the mind where this essence of self resides. as you pointed out already, brain injuries can radically effect a person's personality. (Sam Harris referred to this to great effect in his recent debate on the afterlife. also see a recent essay in Slate by Jesse Bering). we know that consciousness doesn't reside in one place in the brain because injury or disease effecting one region of the brain can radically change a person's personality and their facilities. on the theory that consciousness resides in some center of the brain we should expect that injury and disease might change someone's faculties but that the essence of who they are would remain unchanged. this is not the case.
What constitutes consciousness still remains a scientific mystery but many theories abound.
I am in favor with it residing in the electro magnetic field that is a product of the flow of neuro-transmitters as oppose to being the static construct of the neurons themselves. But since neurons tile space, a-periodically, this leads to complex mathematical constructs in terms of modeling. I believe that Roger Penrose's concepts, in his "Emperor's New Mind", may be at play also. Specifically, quantum mechanics and chaos theory. In short neurons tile space more complex then quasi-crystals, which are little understood by conventional models of crystal grows and introduce the impossible five fold symmetry in defiance of conventional wisdom. Thus Penrose conjectures that a quantum mechanical wave existing in Hilbert space collapses and give rise to crystals knowing where they are going before they get there. Thus actually have a physical testable system to demonstrate that there is a higher reality to existence that we are oblivious of. Event space in which we live, thus is not the absolute perception of reality.