50 things I need to know ( As opposed to see) before I die ....

To have passed on, not knowing the truth about religions and gods would have been terrible.

The current size And age of the universe

The discovery of plate tectonics


The discovery of the DNA helix


What are the next 46 in your opinion?

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Your list seems more like "50 Things Everyone Should Learn About". If that's the topic, I'd add things like:

 - the scientific method

 - how to identify logical fallacies

 - how to separate fact from fiction

 - understanding statistics and probability

 - evolution

 - disease theory

 

However, if you want "50 Things I'd Like to Learn Before I Die" (which seems more in line with how you named the list) then I wouldn't include things that are already well known like DNA or size of the universe. Instead I'd want to learn things like:

 - are humans alone in the universe?

 - where is the nearest extra-terrestrial life? intelligent life? what's it like?

 - how to travel in time

 - how to travel beyond our solar system

 - where is the nearest planet that can sustain human life?

 - how to live peacefully & sustainably on the earth

 - the cure for cancer, heart disease, etc.

 - how to extent human life indefinitely

 

Etc, etc.

 

 

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